Van de Ven Double Ends Everton's Unbeaten Streak at Brand New Stadium
The Dutch defender emerged as the first backline player to net two goals in a English top-flight match for Tottenham since Jan Vertonghen in March 2013.
At a glance
Micky Van de Ven nods into the net two times in opening period
The home side's Jake O'Brien has equalizer disallowed after video check
Senegalese midfielder nets third in 89th minute
The defeat is the Merseyside club's initial at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Spurs prolonged their unbeaten run in away games in the Premier League and delivered the Toffees their initial loss at Hill Dickinson Stadium.
Everton were undefeated in their last five matches at their new ground at Bramley-Moore Dock, having left their historic home behind after more than a century at the conclusion of the previous campaign.
But Tottenham's leader the Dutchman struck twice from set-pieces in the opening 45 minutes to place their strong form at jeopardy, and they were failed to mount a comeback before the midfielder - set up by former Toffees attacker Richarlison - nodded in a third to put the game to bed.
The Everton defender believed he had levelled the tally five minutes after the defender's first goal, directing a bullet header past the Spurs keeper from an set-piece.
Beto, in the meantime, missed a number of chances, while Vicario made a series of excellent stops to ensure Tottenham went five matches on the road unbeaten in the Premier League.
But the VAR stepped in, advising Craig Pawson to check the score on the pitchside monitor and the official decided that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory moves Thomas Frank's team up to third in the division, five points off north London rivals and table-toppers the Gunners.
Everton stay in 14th position and sit half a dozen points clear of the relegation zone.
Spurs breakdown: The defender excels in role at both ends of pitch
Following a drab midweek performance in the European competition against the French side, where they mustered a mere attempts on target, the manager opted for the French striker up front instead of ex-Everton forward the Brazilian.
The summer signing was unable to influence the game before being substituted for the substitute after 60 minutes on the pitch, but it emerged he wasn't needed in the final outcome.
Defender Van de Ven transformed into an attacking force to be feared.
Tottenham's first goal came from a cleverly executed set-piece play, with the midfielder directing the ball toward the face of goal for an free Van de Ven to score.
And the captain - stepping up as skipper in Cristian Romero's absence - added his next goal in added time as he outjumped the England keeper to head home.
The Dutchman was equally impressive in defence, combining effectively with his defensive colleague as the pair handled superbly with the 34 crosses thrown their way by the opposition.
Everton analysis: Everton missing striker's instinct
The club's new home had been a happy hunting ground, but it appears the novelty may have faded slightly and supporters headed to the gates after Sarr's final goal for Tottenham.
The end in the team's winning streak at home won't be a major concern for David Moyes, but their striker situation are.
The forward and Thierno Barry - the Toffees' pair of established centre-forwards - had scored just one league goal between them before the weekend's outing.
And they were unable to contribute to that miserable tally on a damp and dreary evening on in Liverpool.
The striker's performance was epitomized when he chose to overhead kick a golden opportunity from close range, even with having space and time to reposition for a more conventional attempt that would have tested the keeper.
The substitute, too, was unable to make an impact after replacing the starter in the 65th minute.
It was not for a shortage of opportunity. Most of Everton's attacks came through the winger and Ndiaye, who relentlessly delivered threatening balls into the Tottenham penalty area.
Upcoming fixtures for both teams?
Everton: The team head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: The London club travel to St James' Park on Wednesday, 29 October for their fourth-round Carabao Cup tie against Newcastle.